A Comparison of Zidovudine (AZT) and Stavudine in HIV-Infected Patients
Status:
Completed
Trial end date:
1994-12-01
Target enrollment:
Participant gender:
Summary
To compare stavudine (d4T) and zidovudine (AZT) in slowing the progression of HIV disease. To
compare the antiviral activity of d4T versus AZT as measured by plasma levels of p24 antigen
and HIV viremia, and their relative efficacy by improvement and/or absence of adverse changes
over time in laboratory parameters associated with HIV infection. To compare the safety of
oral doses of d4T to AZT in patients with HIV infection.