A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcers

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Esomeprazole plus aspirin compared with esomeprazole alone for the treatment of aspirin-related peptic ulcers.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kaohsiung Veterans General Hospital.
• Treatments: Aspirin; Esomeprazole

Criteria

Inclusion Criteria:

• aspirin users who have a peptic ulcer confirmed by endoscopy

Exclusion Criteria:

• serious medical illness (including cardiovascular events within 6 months before endoscopy)

• acute gastrointestinal bleeding

• a history of gastric or duodenal surgery

• allergic to the study drugs

• require long-term treatment with non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), antiplatelet agents, or anticoagulant agents

• pregnancy