Overview

A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy

Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
HIV infected children and adolescents who have taken many anti-HIV drugs may have limited treatment options and are at high risk for progressing to AIDS. The purpose of this study is to determine whether an anti-HIV treatment regimen of 2 protease inhibitors (PIs) and 2 nucleoside reverse transcriptase inhibitors (NRTIs) is more effective than a regimen of 4 NRTIs in treatment-experienced children and adolescents who have failed previous anti-HIV treatment.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Abacavir
Emtricitabine
Lamivudine
Lopinavir
Ritonavir
Saquinavir
Tenofovir
Zidovudine