A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block

• Status: Completed
• Trial end date: 2016-08-20
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this randomized, observer-blinded study is to evaluate the postoperative analgesic efficacy of adding dexamethasone and clonidine to ropivacaine in supraclavicular nerve block. The investigators hypothesized that addition of dexamethasone and clonidine to ropivacaine would prolong the duration of analgesia in supraclavicular nerve block compared with ropivacaine alone.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Texas Southwestern Medical Center
• Treatments: BB 1101; Clonidine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• Men and women 18-80 years old

• Undergoing upper extremity surgery

• Receiving Supraclavicular block

• Receiving ropivacaine, ropivacaine adjuvants (dexamethasone, clonidine) for the supraclavicular nerve block.

• Able to give Informed consent

Exclusion Criteria:

• Age less than 18 and greater than 80 years

• Inability to understand the study procedures

• Significant respiratory dysfunction

• Preexisting neurologic deficits

• Allergy to local anesthetics

• A bleeding diathesis or on anticoagulants

• Systemic glucocorticoid use

• Refuse to participate in the study