Overview

A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair

Status:
Recruiting
Trial end date:
2021-02-02
Target enrollment:
60
Participant gender:
All
Summary
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group) received two placebo tablets and an injection of ketamine at a dosage of 0.15 mg/Kg before induction of spinal anesthesia.. During the surgery, blood pressure and heart rate were monitored. Postoperative analgesia was provided by a PCA morphine. Acute postoperative pain was assessed by a visual analog scale. The incidence of postoperative neuropathic pain was detected by the DN4 questionnaire after one and three months of surgery.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University Tunis El Manar
Treatments:
Gabapentin
Ketamine
Criteria
Inclusion Criteria:

- ASA I and II

- Inguinal Hernia Repair in non emergent conditions

Exclusion Criteria:

- Patients with significant cardiovascular central nervous system disease, renal or
liver failure could not operate the PCA device