Overview

A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium

Status:
Completed

Trial end date:
2008-11-01

Target enrollment:

Participant gender:

Summary

The purpose of the study is to determine whether dexmedetomidine is a more effective medication than haloperidol in the treatment of agitation and delirium in patients receiving mechanical ventilation in an intensive care unit. Haloperidol is a medication conventionally used for this purpose. The investigators will study only patients who have recovered from their illness to the point that, were it not for agitation and delirium, they would no longer require mechanical ventilation. The investigators hypothesize that patients receiving dexmedetomidine will be able to discontinue mechanical ventilation earlier than those receiving haloperidol.

Phase:

Phase 2

Details

Lead Sponsor:

Austin Health

Collaborator:

The Alfred

Treatments:

Dexmedetomidine
Haloperidol
Haloperidol decanoate