A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries.

• Status: Completed
• Trial end date: 2022-12-05
• Target enrollment: 0
• Participant gender: All

Summary

To compare the effects of using different doses of intrathecal hyperbaric prilocaine 2% combined with fentanyl 25 µg in patients scheduled for a day-case lower abdominal and urologic surgery in the geriatric patient population.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Collaborators: Ahmed Abdullah Fathi Mohamed Almadawi; Hagar Hassanein Refaee; Norhan Abdel Aleem Ali

Criteria

Inclusion Criteria:

• Age (65 - 80)

• ASA I - III

• Both genders.

• Height (1.60-1.90) m.

• BMI (18.5-40) kg m-2

• Scheduled for elective day-case lower abdominal or urologic procedures < 90 minutes in duration under spinal anesthesia.

• Type of surgery: Inguinal, femoral and incisional herniorrhaphies, bilateral varicocelectomies, hydrocelectomy, lymph node biopsies and mass excision biopsies, TURP surgery, Cystoscopies, ureteroscopy, bladder stone extraction, DJ insertion.

Exclusion Criteria:

• Patients requiring general anesthesia.

• Operations requiring sensory block above T10.

• Known or suspected coagulopathy (international normalised ratio > 1.4), thrombocytopenia (platelet count < 100,000).

• Known peripheral neuropathy, neurological deficits or skeletal deformities.

• Known allergy to prilocaine.

• Infection at site of injection.

• Patients' refusal to sign informed consent.

• Patients 'not meet inclusion criteria.