A Comparative Study of Rosuvastatin and Atorvastatin in Patients With Hyperlipidemia

• Status: Unknown status
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will be conducted to assess the status of oxidative stress inflammation and thrombogenesis in patients with hyperlipidemia and to compare the antioxidative, anti-inflammatory and antithrombogenic effects of rosuvastatin and atorvastatin.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
• Treatments: Atorvastatin; Atorvastatin Calcium; Rosuvastatin Calcium

Criteria

Inclusion criteria:

• Age from (20-75) yrs, both male and female having LDL cholesterol: 160-190 mg/dl, triglyceride (TG): 200-499 mg/dl will be recruited in the study

Exclusion criteria:

• Patients age <25 years or >75 years

• Patients are on lipid lowering medications

• Patients taking omega-3 fatty acid or garlic

• Patients with history of hypersensitivity on any member of statin

• Patients taking anti-inflammatory medications (steroid or NSAIDS)

• Patients taking antioxidant vitamins (vitamin A, C, E)

• Patients with impaired renal function

• Patients with impaired liver function

• Pregnant women and nursing mother

• Patients having serious infections or terminal illness