A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated Intra-abdominal Infections

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

On the basis of monotherapy for intra-abdominal infection, the investigators are conducting this study to identify the difference of drug efficacy between ampicillin/sulbactam and moxifloxacin.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
• Treatments: Ampicillin; Fluoroquinolones; Moxifloxacin; Norgestimate, ethinyl estradiol drug combination; Sulbactam; Sultamicillin

Criteria

Inclusion Criteria:

• patients diagnosed of complicated intra-abdominal infection need surgical treatment

Exclusion Criteria:

• patients diagnosed of intra-abdominal infection receive non-operative management

• patients with known allergic history of fluoroquinolone

• Severe, life threatening disease with a life expectancy of < 48 h or APS and APACHE scores of > 35