Overview

A Cluster-randomized Cross-over Trial Evaluating the Comparative Effectiveness of Three Skin Antiseptic Interventions

Status:
Completed
Trial end date:
2009-11-01
Target enrollment:
0
Participant gender:
All
Summary
Background: Contaminated blood cultures result in unnecessary antibiotic use, increased length of stay, and additional laboratory tests, all of which increase healthcare costs. While the optimal skin antisepsis agent for reducing blood culture contamination is not known, the cost of various agents differs substantially. Objective: To determine the relative rates of blood culture contamination for 3 skin antisepsis interventions - 10% povidone iodine aqueous solution (PI), 2% iodine tincture (IT) and 2% chlorhexidine gluconate in 70% isopropyl alcohol (CHG) - when used by dedicated phlebotomy teams to obtain peripheral blood cultures in adult non-ICU medical and surgical patients.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Michigan
Collaborator:
Blue Cross Blue Shield of Michigan Foundation
Treatments:
Anti-Infective Agents, Local
Cadexomer iodine
Chlorhexidine
Chlorhexidine gluconate
Ethanol
Iodine
Povidone
Povidone-Iodine
Criteria
Inclusion Criteria:

- Patient on general medical, surgical, and cardiology floors

- Receipt of a peripheral blood draw for blood culture collection

- Blood draw performed by phlebotomy team

Exclusion Criteria:

- None