A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis

• Status: Completed
• Trial end date: 2014-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study investigates the effective power of angina pectoris after Quick-Acting Heart Reliever and isosorbide dinitrate interventing respectively the patients with moderate coronary stenosis for six months. At the same time, the studying will assess the plaque, myocardial blood-supplying,quality of life and observe the end point of the heart (including the myocardial revascularization, death and myocardial infarction). The purpose is to study the function of the blood-quickening stasis-transforming formula Quick-Acting Heart Reliever for moderate coronary stenosis lesions.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
• Treatments: Aspirin; Isosorbide; Isosorbide Dinitrate; Isosorbide-5-mononitrate

Criteria

Inclusion Criteria:

• Male or female subjects 30-75 years of age

• Angina or CAD patient

• Diameter stenosis 50-75% in at least one main coronary artery (Confirmed by coronary arteriography or coronary CT angiography)

• Not received percutaneous coronary intervention(PCI)

• Heart blood stasis obstruction syndrome according to TCM syndrome differentiation

• Provide written informed consent.

Exclusion Criteria:

• Heart transplant or history of CABG or history of percutaneous transluminal coronary angioplasty (PTCA) with a drug-eluting stent.

• Left ventricular ejection fraction < 35%

• Acute myocardial infarction within 4 weeks prior to inclusion

• The contractive pressure > 160 mmHg or diastolic pressure >100 mmHg

• Severe valvular heart disease

• Insulin-dependent diabetes mellitus

• Serious heart, lung, liver, kidney and brain or other primary complications

• Mental patients

• Diagnosed or suspected tumor

• Allergic persons

• Pregnant, breastfeeding, or intends to become pregnant during the course of the study (females only)

• Patients not willing to or not able to give the informed consent to participate in the study

• The patients who are attending other clinical trial

• The person maybe loss for some reason such as work or life condition according to the investigator's judgement