A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis
Status:
Recruiting
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The study will follow a parallel arm, randomised, double blinded, placebo controlled design.
There will be two groups Group 1 = receiving 1% curcumin chips after routine scaling and root
planing (n=20) Group 2 = receiving placebo chips after routine scaling and root planing
(n=20) Clinical parameters: ( Baseline, 4 weeks, 12 weeks) Probing pocket depth, clinical
attachment level, gingival index, plaque index Cytokine parameter ( Baseline, 4 weeks)
Interleukin 1 beta in GCF
Statistical analysis Repeated measures of ANOVA Paired t-tests