A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
Status:
Recruiting
Trial end date:
2022-08-01
Target enrollment:
Participant gender:
Summary
Postoperative delirium is one of the most frequent adverse events following elective
non-cardiac surgery and is associated with cognitive impairment at discharge, as well as
in-hospital and long-term mortality, however, despite being a well-recognized problem there
is a dearth of effective interventions for prevention and management. A modifiable risk
factor associated with postoperative delirium is poor postoperative pain control, and by
improving the pain regimen the investigators may be able to decrease the incidence and/or
severity of postoperative delirium. In this study, the investigators seek to study whether a
postoperative intravenous infusion of lidocaine, known to improve pain control in other
contexts, can decrease the risk of postoperative delirium and other opioid-related side
effects, following major reconstructive spinal surgery.