This project is designed to test the hypothesis that inhibition of binding between tumor
necrosis factor alpha (TNF-alpha) and its receptors using Remicade (infliximab, chimeric
mouse/human IgG1K monoclonal antibody directed against human TNF-alpha, Centocor, Malvern,PA)
is clinically useful for patients with uveitis that is refractory to other forms of systemic
immunosuppressive therapy.