A Clinical Pharmacological Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
To investigate the pharmacokinetics, pharmacodynamics (urine volume and fluid intake),
efficacy(body weight, pulmonary congestion and other congestions including cardiothoracic
ratio) and safety of 7-day repeated oral administration of OPC-41061 at 7.5 mg or 15 mg in
congestive heart failure (cardiac edema) patients with extracellular volume expansion despite
the use of a diuretic.