A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIA

• Status: Completed
• Trial end date: 2021-05-18
• Target enrollment: 0
• Participant gender: All

Summary

Investigators aim to determine the optimal dose of granisetron in strabismus ophthalmic surgeries under general anesthesia to prevent postoperative nausea and vomiting

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Collaborators: Islam Mohamed Sayed; Mohamed Yousry Mohamed; Mohamed, Ahmed A., M.D.; Tamer Fayez Safan; Tamer Mohamed Khair
• Treatments: Granisetron

Criteria

Inclusion Criteria:

• • Adult patients > 18 years old.

• ASA I and II.

• Patients scheduled for strabismus surgery.

Exclusion Criteria:

• • ASA class > II.

• Patients with known hypersensitivity or contraindication to any of the study medications.

• Patients who had chronic nausea and vomiting or experienced retching, vomiting, moderate to severe nausea in the preoperative day.

• Patients who had received an antiemetic drug in the preoperative day.

• Patients with a body mass index ≥36.

• Pregnant or breast feeding female patient.

• Patients with gastrointestinal diseases.

• Patients with a history of motion sickness, diabetes mellitus, and GIT pathology (gastritis, hematemesis, peptic ulcer).