Overview

A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

Status:
Completed
Trial end date:
2021-04-19
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of macitentan at steady state on the pharmacokinetic (PK) of a single dose of riociguat and sildenafil (Part A); and rosuvastatin (Part B) when co-administered to healthy male participants under fasted conditions.
Phase:
Phase 1
Details
Lead Sponsor:
Actelion
Treatments:
Macitentan
Riociguat
Rosuvastatin Calcium
Sildenafil Citrate
Tadalafil