7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events
Status:
Recruiting
Trial end date:
2021-12-30
Target enrollment:
Participant gender:
Summary
Over 40 million Americans take statins to reduce their risk of atherosclerotic cardiovascular
disease (ASCVD). Unfortunately, 10 to 20% stop taking them due to statin-associated muscle
symptoms (e.g. pain, aches, weakness, cramps, or stiffness) (1, 2). The pathophysiology of
these statin-associated muscle symptoms (SAMS) has remained elusive. Consequently, no
objective diagnostic method exists, causing confusion for patient and providers since muscle
symptoms can often be multifactorial.