7-hydroxystaurosporine and Cisplatin in Treating Patients With Advanced Malignant Solid Tumors
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Phase I trial to study the effectiveness of combining UCN-01 with cisplatin in treating
patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to
stop tumor cells from dividing so they stop growing or die. UCN-01 may stop the growth of
tumor cells by blocking the enzymes necessary for tumor cell growth and may help cisplatin
kill more cancer cells by making tumor cells more sensitive to the drug.