Overview

7% Hypertonic Saline for Acute Bronchiolitis

Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Research suggests that hypertonic saline may improve mucous flow in infants with acute bronchiolitis. Data suggest a trend favoring reduced length of hospital stay and improved pulmonary scores with increasing concentration of nebulized solution to 3% and 5% saline as compared to 0.9% saline mixed with epinephrine. To our knowledge, 7% hypertonic saline has not been previously investigated. OUr hypothesis was that 7% hypertonic saline would improve bronchiolitis severity scores and admission rate.
Phase:
Phase 4
Details
Lead Sponsor:
Le Bonheur Children's Hospital
Treatments:
Epinephrine
Epinephryl borate
Racepinephrine