68Ga-P16-093 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Prostate Cancer Patients

• Status: Recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: Male

Summary

Prostate-specific membrane antigen (PSMA)-targeted PET imaging with 68Ga-labeled compounds is able to provide superior sensitivity and specificity to detect primary prostate tumor and its metastases, like the most widely studied 68Ga-PSMA-11. This pilot study was prospectively designed to evaluate the diagnostic value of 68Ga-P16-093, a novel radiopharmaceutical targeting PSMA, which was compared with 68Ga-PSMA-11 in the same group of prostate cancer patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Peking Union Medical College Hospital
• Treatments: Edetic Acid; Gallium 68 PSMA-11

Criteria

Inclusion Criteria:

• histologically confirmed treated or untreated prostate cancer patients;

• 68Ga-PSMA-11 and 68Ga-P16-093 PET/CT within two consecutive days;

• signed written consent.

Exclusion Criteria:

• known allergy against PSMA;

• any medical condition that in the opinion of the investigator may significantly interfere with study compliance.