2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Status:
Completed
Trial end date:
2018-12-31
Target enrollment:
Participant gender:
Summary
Surgical site infection (SSI) following spinal surgery is a frequent complication and results
in higher morbidity, mortality and healthcare costs. SSI following adult spinal surgery is a
frequent complication that has been reported to occur in 0.7-12.0% of patients and result in
higher postoperative morbidity, mortality and health care costs. Vanderbilt University
Medical Center SSI rate is 7%. Treatment for SSI can be challenging often requiring revision
surgery, long-term antibiotics, and prolonged hospitalization. The accurate identification of
risk factors is thus important in the development of strategies to prevent these potentially
devastating infections. This study proposes a randomized, controlled trial of neuro-spine
patients of 2% chlorhexidine gluconate skin preparation cloths for the prevention of post op
surgical site infections in spine patients.
Use of CHG cloths the night before and morning of surgery (neckline to toes) will affect
(decrease rates) of SSI compared to patients who receive routine standard of care (soap and
water pre-op, day of surgery and daily post-operative).