2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament

• Status: Unknown status
• Trial end date: 2021-11-09
• Target enrollment: 0
• Participant gender: All

Summary

This is a Pilot Phase III single-blind randomized controlled clinical trial in patients, aged 18 years and older, presenting with symptoms of apical periodontitis. The overall goal is to assess whether 2% Chlorhexidine (CHX) is superior to Calcium Hydroxide in reducing interappointment pain.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Southern California
• Treatments: Calcium; Calcium, Dietary; Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion Criteria:

• 18 years and older

• symptomatic apical periodontitis (positive to the bite test)

• restorable tooth

• requires root canal therapy

• able to undergo informed consent process

• must be English or Spanish speaker

Exclusion Criteria:

• Cracked tooth

• non-restorable tooth

• no pain medication or antibiotic taken in the past 3 days