18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone
Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
18 F-fluoride Positron emission tomography (PET) is able to demonstrate and quantify the
metabolic activity locally in the skeleton (1). This technique should, therefore, also be
able to demonstrate a dramatic decrease in the metabolic activity in localized monostotic
Paget's disease lesions after therapy. In this condition, indeed, the usual biological
markers may be unhelpful to assess the efficacy of therapy, because they are usually
comprised in the normal range for single pagetic localizations, even before therapy (2). The
main purpose of this trial is to assess the early and long term response of pagetic bone to
bisphosphonate therapy.
Phase:
N/A
Details
Lead Sponsor:
Université Catholique de Louvain
Collaborators:
FNRS (Belgium) Fonds National de la Recherche Scientifique