Overview

18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules

Status:
Recruiting

Trial end date:
2024-08-01

Target enrollment:
0

Participant gender:
All

Summary

This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with lung nodules. PET imaging with an imaging agent called 18F-FDG is often used in combination with a PET/CT scanner to evaluate cancers. Giving 18F-FSPG before a PET/CT scan may work better in helping researchers diagnose early lung cancer in patients with lung nodules.

Phase:

Phase 2

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Andrei Iagaru
Stanford University

Collaborators:

Boston University
Canary Foundation

Treatments:

Deoxyglucose
Fluorides
Fluorodeoxyglucose F18

Criteria

Inclusion Criteria:

- Pulmonary nodule between the size of 7 to 30 mm. Subjects with multiple nodules may be
eligible if the dominant nodule is 7 to 30 mm

- Undergoing standard of care 18F-FDG PET imaging (for indeterminate pulmonary nodule)

- Current or former cigarette smoker, with >= 20 pack years

- Documented informed consent

Exclusion Criteria:

- History or previous diagnosis of lung cancer

- Cancer diagnosis within the last 5 years

- Pregnant or nursing