18F-FMPP PET MPI in the Detection of Coronary Artery Disease
Status:
Recruiting
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
18F-FMPP is a novel PET myocardial perfusion imaging (MPI) tracer which targets to
mitochondria complex I (MC-I). Preclinical animal studies have shown that its uptake is
highly uniform and long in the heart and rather low in the liver. It may be a promising
tracer for myocardial perfusion imaging. In addition, as a myocardial PET tracer, it is
capable of quantifying absolute myocardial blood flow. Thus this prospective and open-label
study is going to evaluate the diagnosis performance of 18F-FMPP PET MPI in suspected or
known CAD patients who will be referred for invasive coronary angiography (ICA).