17 Alfa Hydroxyprogesterone Caproate Versus Natural Progesterone for the Prevention of Preterm Labor
Status:
Unknown status
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Preterm deliveries play a significant role in neonatal morbidity and mortality. Previous
studies showed that administration of progesterone to pregnant women at high risk, decrease
spontaneous preterm deliveries.
The purpose of this study is to compare between two different modes of treatment with
progesterone for the prevention of preterm delivery: weekly injection of 17 alfa
hydroxyprogesterone caproate versus daily vaginal administration of progesterone in terms of
efficacy, comfort and compliance, safety and cost of treatments.