Overview

1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT

Status:
Terminated
Trial end date:
2009-02-01
Target enrollment:
0
Participant gender:
All
Summary
Parallel, Multi-Center, Double-masked, Active controlled, three arm study comparing the IOP lowering efficacy and safety over 12 months of morning or evening instillations of Travoprost/Brinzolamide vs. Cosopt dosed in the morning and evening in patients with open-angle glaucoma or ocular hypertension.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Alcon Research
Collaborator:
PPD
Treatments:
Brinzolamide
Travoprost
Criteria
Inclusion Criteria:

- IOP at screening visit <18mmHg in at least one eye Mean IOP in same eye (at both
eligibility 1 &2 visits)

- 24 and ≤ 36 mmHg at 9:00

- 21 and ≤ 36 mmHg at 11:00 and 16:00

Exclusion Criteria:

- Severe central visual field loss Angle Shaffer grade < 2 C/D ratio > 0.8 (horizontal
or vertical measurement)