Overview

1% Metformin in Moderate and Severe Periodontitis

Status:
Completed

Trial end date:
2014-08-01

Target enrollment:
0

Participant gender:
All

Summary

This study evaluates the efficacy of 1% Metformin gel in treatment of moderate and severe periodontitis subject.

Phase:

Phase 2/Phase 3

Accepts Healthy Volunteers?

Accepts Healthy Volunteers

Details

Lead Sponsor:

Government Dental College and Research Institute, Bangalore

Treatments:

Metformin

Criteria

Inclusion Criteria:

- Systemically healthy subjects, Pocket depth ≥ 5 mm, Clinical attachment level ≥ 4 mm
and vertical bone loss ≥ 3 mm on intraoral periapical radiographs, with no history of
periodontal therapy in the last 6 months.

Exclusion Criteria:

- subjects allergic to MF, those on systemic MF therapy, subjects with aggressive
periodontitis, immunocompromised subjects, use of tobacco in any form, alcoholics,
lactating and pregnant females.