Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

• Status: Completed
• Trial end date: 2021-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

The primary objective is to determine if pre-operative transversus abdominis plane (TAP) nerve blocks by continued infusion of local anesthetic post-operatively affects post-operative narcotic usage, as compared to a placebo TAP block, after breast reconstruction surgery.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University
• Treatments: Acetaminophen; Bupivacaine; Hydromorphone; Ondansetron; Oxycodone

Criteria

Inclusion Criteria

• Prior diagnosis or presumed diagnosis of breast cancer or undergoing prophylactic treatment.

• Greater than 18 years old.

• Female.

• Undergoing microsurgical breast reconstruction with abdominal free flap.

• Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria

• True allergy to local anesthetics or opioids.

• History of addiction to narcotics within the last 24 months

• History of chronic pain on opioids within the last 24 months.

• Specific mental health issues such as schizophrenia or bipolar disorder.

• Patients who are pregnant.