The Efficacy and Safety of Ramosetron in Patients Undergoing Off Pump Coronary Artery Bypass Surgery

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the effects of ramosetron on corrected QT interval in patients undergoing off pump coronary artery bypass surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Anesthetics; Ramosetron

Criteria

Inclusion Criteria:

• Elective off-pump coronary artery bypass graft surgery

Exclusion Criteria:

• Emergency operation

• preoperative use of any inotropics or mechanical assist device

• severe liver disease (>Child class II)

• dialysis dependent renal failure

• Left ventricular ejection fraction <30 %

• Combined major surgery like carotid endarterectomy

• Previous allergy history to any 5-hydroxytryptamine type 3 (5-HT3) antagonist

• Preoperative QT prolongation ( 500 >msec) or arrhythmia