The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
Myocardial dysfunction necessitating inotropic support is a typical complication after
on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and
renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support
after coronary-artery-bypass-grafting. With respect to data derived from patients with sepsis
shock and results from studies using phosphodiesterase-inhibitors prophylactically, the
hypothesis is tested that adrenaline may be associated with unwarranted metabolic effects
(hyperlactatemia and hyperglycemia) and renal dysfunction.