Overview

Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients

Status:
Unknown status
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
It is well known that ICU patients need sedation. Now no ideal sedation drug existed and every sedation drug has its advantage and disadvantage,so combined sedation may use the advantage and avoid the disadvantage of the sedation drug according to the patients'condition. Until now, there is rare study about the combined sedation or sequenced sedation of different sedation drug.The purpose of the study is to explore the value of combined sedation with midazolam and dexmedetomidine compared to single drug sedation in ICU, so as to seek an ideal sedation protocol that could reduce the cost of treatment,obtain the appropriate sedation not under sedation or over sedation,reduce the incidence of delirium, reduce the adverse event of sedation.
Phase:
Phase 4
Details
Lead Sponsor:
Qilu Hospital
Qilu Hospital of Shandong University
Collaborator:
Chinese Medical Association
Treatments:
Dexmedetomidine
Fentanyl
Midazolam