Overview

Pilot Study to Evaluate Levodopa as Treatment for Residual Amblyopia

Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
This pilot study is being conducted as a prelude to a randomized trial to compare levodopa/carbidopa plus patching versus patching alone. The purpose of the pilot study is to demonstrate recruitment potential, to provide prospective data on the tolerability of levodopa as a treatment for amblyopia, to provide limited data on its safety, to provide limited data on it's efficiency, and to provide data to assist in selecting a dose to use in a subsequent phase 3 randomized trial. In addition, this study will provide the opportunity for investigators to gain experience in using levodopa prior to a randomized trial.
Phase:
Phase 2
Details
Lead Sponsor:
Jaeb Center for Health Research
Collaborator:
National Eye Institute (NEI)
Treatments:
Carbidopa
Levodopa