Overview

Physical Activity With or Without Dexamethasone in Reducing Cancer-Related Fatigue in Participants With Advanced, Metastatic, or Recurrent Cancer

Status:
Recruiting

Trial end date:
2022-05-31

Target enrollment:

Participant gender:

Summary

The goal of this clinical research study is to learn about the effects of combining physical activity with dexamethasone to treat fatigue in patients with advanced cancer. In this study, dexamethasone will be compared to a placebo. A placebo is not a drug. It looks like the study drug but is not designed to treat any disease or illness. It is designed to be compared with a study drug to learn if the study drug has any real effect. This is an investigational study. Dexamethasone is FDA approved and commercially available for the treatment of loss of appetite, tiredness, pain, and nausea. It is investigational to combine dexamethasone and exercise to treat fatigue in advanced cancer patients. The study doctor can explain how the study drug is designed to work. Up to 70 participants will be enrolled in this study. All will take part at MD Anderson.

Phase:

Phase 2/Phase 3

Details

Lead Sponsor:

M.D. Anderson Cancer Center

Collaborators:

National Cancer Institute (NCI)
National Institute of Nursing Research (NINR)

Treatments:

BB 1101
Dexamethasone
Dexamethasone acetate
Ichthammol