Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone
Status:
Completed
Trial end date:
2006-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the how the body absorbs and processes new forms of oral
testosterone. Information gained during the study may help develop better forms of
testosterone therapy in the future.
We will be administering three drugs. Dutasteride is FDA approved to treat prostate
enlargement. Lupron is approved for treatment of prostate cancer. Testosterone is approved
for treatment of testicular insufficiency. They are being used in this study for "off-label"
research purposes. This study will allow us to find out the effect of food on two
formulations of testosterone taken by mouth, and the relative effect of food on testosterone
absorption.
Information from this study may be useful in treatment of men with low testosterone levels
and the development of a male hormonal contraceptive.
Phase:
Phase 2
Details
Lead Sponsor:
University of Washington
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) GlaxoSmithKline National Institutes of Health (NIH)