Overview

Ondansetron for Bipolar Disorder and Alcohol Use Disorders

Status:
Completed
Trial end date:
2018-05-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine if ondansetron, as an add-on therapy, is associated with reduced depressive symptoms and alcohol use in outpatients with bipolar disorder (BPD), cyclothymic disorder, schizoaffective disorder (bipolar type) and major depressive disorder (MDD) with mixed features. The investigators will also use blood samples to determine if the genotype for the serotonin transporter gene is associated with response to ondansetron.
Phase:
Phase 4
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborator:
Stanley Medical Research Institute
Treatments:
Ethanol
Ondansetron