The purpose of this study is to assess the effectiveness of different malaria control
strategies in the first year of life.
The effectiveness of delivering an intermittent screening and treatment programme with
dihydroartemisinin-piperaquine (DHP), linked to local immunization programmes, will be
compared to the current practice of passive case detection of malaria.
This study has two objectives:
1. To assess the effectiveness of intermittent screening and treatment with
dihydroartemisinin-piperaquine (DHP) administered at 2, 3, 4 and 9 months of age
compared with the current practice of passive detection and treatment for malaria in an
area with high drug resistance levels to both P. falciparum and P. vivax.
2. To evaluate the safety, efficacy and population pharmacokinetics of DHP in children
under 1 year of age.
Phase:
N/A
Details
Lead Sponsor:
Gadjah Mada University
Collaborators:
Eijkman Institute for Molecular Biology Eijkman Institute, Jakarta, Indonesia Menzies School of Health Research Timika Research Facility, Indonesia