Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis
Status:
Completed
Trial end date:
2004-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate whether Biaxin (clarithromycin) improves sputum
abnormalities, lung function, and overall feeling of well-being in people with cystic
fibrosis (CF). Biaxin is an antibiotic commonly used for the treatment of respiratory
infections in people who do not have CF, and is sometimes used in CF patients as well.
Studies done in a disease called diffuse panbronchiolitis (which is similar to CF) and some
preliminary studies that have been done in CF patients suggest that Biaxin might have a
beneficial effect on CF sputum in ways unrelated to its antibiotic activity.