Effect of Fluticasone Furoate/Vilanterol on EIA in Adolescents
Status:
Completed
Trial end date:
2020-04-15
Target enrollment:
Participant gender:
Summary
Exercise induced asthma (EIA) is common in adolescents. (Fluticasone furoate (FF)/Vilanterol
(VI)) is a once daily inhaler with bronchodilator effect lasting 24 hours. Our objective was
to investigate the short and long-term effects of FF/VI on EIA in adolescents. Adolescent
asthmatics were referred for evaluation of EIA. Patients with a positive exercise challenge
test, were allocated to a single administration of salbutamol and 22 to FF/VI in a double
blind, double dummy method to assess the short-term effect on EIA. Then they received FF/VI
for 30-60 days and were reassessed by a repeat exercise test 24-hours after the last dose.