Depomedrol for Genicular Nerve Block.

• Status: Not yet recruiting
• Trial end date: 2023-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to test the efficacy of adding Depomedrol a long-acting steroid to bupivacaine for relieving postoperative pain and reducing opioid requirements following total knee replacement surgery. For this purpose, Depomedrol will be added to bupivacaine for ultrasound-guided Genicular nerve block combined with spinal anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University
• Treatments: Bupivacaine; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Subjects scheduled for primary elective total knee arthroplasty.

• American Society of Anesthesiologists Physical Status I-III.

• BMI 18-35 kg/m2.

Exclusion Criteria:

• Bleeding disorders.

• Allergy to any of the drugs used in the study.

• Renal insufficiency.

• Liver failure

• Neurological abnormalities (uncooperative or psychologically unstable patients).

• Patient refusal.

• Contraindication to a peripheral nerve block.

• ASA IV or V.

• Skin lesions/infection at block site.