Overview

Can Dexmedetomidine For Procedural Sedation In Knee Arthroplasty Reduce Postoperative Pain? A Randomized Control Study

Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
0
Participant gender:
All
Summary
Dexmedetomidine has been often used for procedural sedation. It has also has been shown to have a pain sparing effect. Therefore the investigators propose that if Dexmedetomidine is used for sedation in total knee replacements done under spinal anesthetic, the patients will have less pain up to 24 hours after the procedure.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Saskatchewan
Treatments:
Dexmedetomidine
Criteria
Inclusion Criteria:

- Total Knee arthroplasty American Society of Anesthesiologist score of 1-3 Age 18-85
Elective total knee arthroplasty under spinal anesthetic.

Exclusion Criteria:

- Contraindication to Dexmedetomidine. (second or third degree heart block, renal or
hepatic dysfunction) Contraindication to Spinal Anesthetic Pain being treated by
opioids prior to operation Contraindication to premedication Previous total knee
arthroplasty