Overview

Adalimumab in the Treatment of Chronic Pouchitis

Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
This study wants to investigate the efficiency of biological treatment for chronic pouchitis. Chronic pouchitis is inflammation in a reconstruction after removal of the colon, a pouch. It is examined in patients with ulcerative colitis. The primary objective evaluation is to evaluate the clinically effect of biological therapy (adalimumab) in patients with chronic pouchitis. Secondary objective is to evaluate the effect of biological therapy on the endoscopical and histological inflammatory activity. It is a double-blinded randomized placebo controlled study.
Phase:
Phase 3
Details
Lead Sponsor:
Odense University Hospital
Collaborators:
Aarhus University Hospital
AbbVie
Hvidovre University Hospital
University of Southern Denmark
Treatments:
Adalimumab