A Study to Test the Use of Duloxetine for Pain in MS
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Many patients with Multiple Sclerosis experience pain that is caused by the effects of MS on
the nervous system.
The purpose of this study is to see if an investigational drug (Duloxetine) will reduce pain
in subjects with MS.
The US Food and Drug administration (FDA) has approved this drug for use with depression or
pain from diabetes.However, it is considered investigational for this study because it has
not been approved for patients with MS.
This study will recruit patients with MS who have central pain which is 4 or greater on a
scale of 1-10. Patients must have experienced pain for 2 months or longer prior to begining
the study.The study will last 10 weeks, patients will be randomized either Duloxetine or
placebo and will be carefully monitored throughout the study. Patients will keep pain/sleep
diaries during the study period and will be provided Ibuprofen for pain control.