This study will test the safety of a drug called SGN-B7H4V in participants with solid tumors.
It will also study the side effects of this drug. A side effect is anything a drug does to
your body besides treating your disease.
Participants will have cancer that has spread in the body near where it started (locally
advanced) and cannot be removed (unresectable) or has spread through the body (metastatic).
This study will have three parts. Parts A and B of the study will find out how much SGN-B7H4V
should be given to participants. Part C will use the dose found in Parts A and B to find out
how safe SGN-B7H4V is and if it works to treat solid tumor cancers.