Overview

A Combination of Avelumab and Taxane (AVETAX) for Urothelial Cancer

Status:
Active, not recruiting
Trial end date:
2026-02-23
Target enrollment:
Participant gender:
Summary
This study evaluates the safety and efficacy of the combination of Avelumab, (a fully human anti-programmed death ligand 1 (PD-L1) IgG1 antibody) in combination with a taxane chemotherapy (docetaxel) in patients with metastatic urothelial cancer who are either ineligible to receive cisplatin based chemotherapy, refractory to cisplatin in first line setting or have disease relapse after receiving cisplatin based chemotherapy within a year in the neoadjuvant or adjuvant setting.
Phase:
Phase 1
Details
Lead Sponsor:
Rohan Garje
Collaborators:
Pfizer
University of Iowa
Treatments:
Antibodies, Monoclonal
Avelumab
Docetaxel
Taxane